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Medical preparations of the French pharmaceutical company Servier. Предуктал® MV (Preductal MR) buy in Baku
ALL.BIZ Azerbaijan Azerbaijan products Pharmaceutics Medications Cardiovascular system treatment substances © Cardiovascular preparations Medical preparations of the French pharmaceutical company Servier. Предуктал® MV (Preductal MR)
Buy Medical preparations of the French pharmaceutical company Servier. Предуктал® MV (Preductal MR)
Medical preparations of the French pharmaceutical company Servier. Предуктал® MV (Preductal MR)

Medical preparations of the French pharmaceutical company Servier. Предуктал® MV (Preductal MR)

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Description
Active ingredient
 Trimetazidin * (Trimetazidine *). Trimetazidin prevents decrease in intracellular concentration of ATP by preservation of a power metabolism of cages in a condition of a hypoxia. Thus, the preparation provides normal functioning of membrane ion channels, transmembrane transfer of ions of potassium and sodium and preservation of a cellular homeostasis.
Trimetazidin inhibits oxidation of fatty acids at the expense of selective inhibition of enzyme 3-ketoatsil-KOA-tiolazy (3-KAT) of a mitochondrial tritsepochechny isoform of fatty acids that leads to glucose oxidation strengthening, including and owing to glycolysis acceleration, as causes protection of a myocardium against ischemia. Switching of a power metabolism from oxidation of fatty acids on oxidation of glucose is the cornerstone of pharmacological properties of a trimetazidin.
It is experimentally confirmed what trimetazidin possesses the following properties:
- supports a power metabolism of heart and neurotouch fabrics during ischemia;
- reduces expressiveness of intracellular acidosis and the changes of a transmembrane ionic stream arising at ischemia;
- lowers the level of migration and an infiltration of polynuclear neutrophils in ischemic and reperfuzirovanny tissues of heart;
- reduces the amount of injury of a myocardium;
- does not make direct impact on haemo dynamics indicators.
At patients with stenocardia trimetazidin:
- increases a coronary reserve, thereby slowing down approach of the ischemia caused by physical activity since 15th day of therapy;
- limits the fluctuations HELL caused by physical activity without considerable changes of ChSS;
- considerably reduces the frequency of attacks of stenocardia and need for reception of nitroglycerine of short action;
- improves sokratitelny function of the left ventricle at patients with ischemic dysfunction.

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Medical preparations of the French pharmaceutical company Servier. Предуктал® MV (Preductal MR)
Medical preparations of the French pharmaceutical company Servier. Предуктал® MV (Preductal MR)
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