- Country of manufactureKazakhstan
Tricalcium phosphate - is the most common calcium-phosphorus additive used in animal husbandry practice in many countries. Tricalcium phosphate and now considered the most common "feed phosphates." Included in the minerals - phosphorite, apatite, gidroksilapatita.Trikaltsiyfosfat is according to various sources gray or gray with brown tint, cream or pale yellow, white with gray shade amorphous powder poorly soluble in water. Such a variation in color tone features of the product in question - the result of irregular chemical composition of the feedstock of individual deposits of apatite from which the trikaltsiyfosfat.Plotnost: 2.81 g / cm³. The melting point of 1670 ° C.Poluchayut hydrothermal roasting apatite or phosphorite concentrate with the addition of the hemihydrate phosphoric acid at a temperature of 1450-1600 ° C.Otnositelno cheap tricalcium phosphate can be considered as the most valuable and effective source of minerals for the animal organism with its relatively low price. Its use as a feed additive in the composition of compound feeds and feed mixtures, allows you to easily balance the levels of phosphorus in the diets of all kinds of agricultural animals and significantly raise productivity zhivotnyh.Trikaltsiyfosfat used also for purification of sugar syrups in the production of refined sugar in the production of ceramics and glass, for manufacturing toothpastes and powders, it is part of abrasives for polishing and grinding metals, is used to remove fluorine from the water conditioner salt, is used in medicine and others. Food tricalcium phosphate is used to eliminate the hygroscopic sodium salt thereof can depending on the kind of raw material, composition of calcium phosphate and destination is available in three grades:
- - Monobasic;
- - Dicalcium phosphate (precipitate);
- - Tricalcium phosphate.
Tricalcium phosphate feed - is a gray or gray with brown tint, cream or pale yellow, white with gray shade amorphous powder. Such a variation in color tone features of the product in question - the result of irregular chemical composition of the feedstock of individual deposits of apatite from which the tricalcium phosphate. The final product contains about 93% chemically pure composition of minerals in trikaltsiyfosfata.Vhodit - phosphorite, apatite gidroksilapatita.Drugie name: tricalcium phosphate, monocalcium phosphate, dicalcium phosphate precipitate is calcium phosphate, calcium phosphate feed, trёhzameschёnny calcium phosphate, calcium orthophosphate, calcium salt of phosphoric acid , calcium phosphate, tehn. titles. - Defluorinated phosphate.
Get gidrotermich. roasting apatite or phosphorite concentrate with additive hemihydrate phosphoric acid H 3 PO 4 (8.6% P 2 O 5 ) at 1450-1600 ° C.Trikaltsiyfosfat produced from the apatite contains at least 34% Ca and 18% P, from phosphorite - at least 30% Ca and 12% P; content F, As and Pb may not exceed resp. 2.10-1, 2.10-4 and 2.10-3% (Composition: Ca: 30-34% P 2 O 5 : 29-41%).
Application. General information.
Natural tricalcium phosphate, in the form of bone and bone ash coal is used, similar to the precipitate and tricalcium phosphate derived from superphosphate, for feeding livestock and poultry.
This is the most common calcium-phosphorus additive traditionally used in animal husbandry practice. Used as a mineral feed (for enrichment and balance of diets of farm animals, including birds, calcium and phosphorus) in the production of animal feed, as phosphorus-containing fertilizers for all vegetable, fruit and ornamental kultury.Dolgie years tricalcium phosphate was practically the only widespread feed phosphates. Such traditions in the use of TCP allow some experts even now equate the term "feed phosphates" with only one of their kind - trikaltsiyfosfatom.Trikaltsiyfosfat used also for purification of sugar syrups in the production of refined sugar in the manufacture of ceramics and glass, for the manufacture of dental pastes and powders, it is part of the abrasives for polishing and grinding of metal, serves to remove fluoride from water conditioning salt, is used in medicine and dr.Mineralny tricalcium allerenny absolutely not aggressive and is not rejected by the body. These properties have been used in medical transplantation, prosthetics, dental and jaw hirurgii.On has a mild cleaning and polishing properties. Its use is associated with the ability to mix well with diammonium pastes containing ammonium compounds. Food tricalcium phosphate is used to eliminate hygroscopic salt.
The use in animal husbandry.
Today worldwide balanced diets of animals and birds taking into account the ratio of phosphorus and calcium. This allows for a more economical use of the additive and avoid overdose. Excessive phosphorus content increases feed consumption, reduces the reproductive function and makes manure and slurry environmentally hazardous. The ratio of calcium and phosphorus in tricalcium perfectly balanced for animals, because in the body of these elements is the ratio 2: 1. It is no coincidence, because the bone - the main depot of calcium and phosphorus - they are found in the form of tricalcium phosphate. What makes it the most effective use of both households and producers kombikormov.Fosforno-calcium feed supplement, which has about 100% water soluble phosphorus is good for all kinds of animals, because for their full feeding requires not only protein, fats, carbohydrates and vitamins and minerals veschestva.Effektivnost its use in livestock because inorganic phosphorus is absorbed by the animals as well as organicheskogo.Primenenie feed phosphates increases the usefulness of feeding the animals and increases the their productivity (daily weight gain, meat quality, milk production). Its degree of assimilation quite high (around 92%) and much less dependent on the diet, age and other factors. Introduction to the diet of feed phosphates prevents diseases associated with lack of macro data, provide proper metabolism in the body, and therefore, the effective functioning of the immune and reproductive sistem.I calcium, and phosphorus play a huge role in the life of the organism.
As a result, daily use of feed phosphates in animal nutrition contributes to:
- - Normalization of mineral metabolism;
- - Increased productivity;
- - Reduction of the fattening period;
- - Obtain healthy offspring (reduces the incidence of animals);
- - The preservation of young animals and the prevention of rickets;
- - Improving the nutritional value of meat, milk;
- - Reduction of feed consumption and, ultimately, increase farm yields (and lower the cost of livestock production).
It provides mineralization of skeleton in animals and birds within the physiological range and penetration into the muscles of animals and birds a greater amount of crude protein, namely 22,9% in the original moisture. When using tricalcium phosphate, feed costs are reduced by 1 kg of live weight gain of 4%, which provides better konversiyu.Tak, adding feed phosphates to DOS. feeds an average increase: cows milk yield by 8-12%; daily weight gain of calves in the 7-12% (with a decrease in the gain unit feed costs by 7-11%); pigs for 8-12%; wool clip in sheep by 5-9%; egg-laying hens 10-15% The amount of phosphates in diets feed depends on the species, age, weight and animal performance. Feed phosphates recommended feed in admixture with concentrates or fodder yeast, silage zhomom, milled root crops from small doses, and during 5 days for complete transfer normu.Fosfaty effective amid senazhnokontsentratnyh diets when excess calcium is fixed natural background in the diet. Particularly strong effect of mineral imbalance manifested in the spring and when added excessively in the diet of beet pulp. Experienced animal science and scientists know that the wealth of phosphorus in the meager rations of nutritionally spring ensures that the live weight of the cows and prepare the animal for intensive milk production in the summer. For example, the daily villa cows to 80-100g tricalcium phosphate for 1.5-2 months of the transition period, the spring provides the effect of keeping the body weight, it does not allow for milking animals, allowing cows to provide increased productivity by at least 10-14% of that laktatsiyu.To phosphates are soluble suggests that phosphorus becomes more available to the body, for example dissolved in a 2% solution of citric acid, it is absorbed almost 100%. The most ideal for digestion usvaivaimost birds and animals grit gives tricalcium phosphate dissolved in a weak solution of citric acid. The ratio of phosphorus and calcium regulates the balance of the diet of birds and animals, whereby it is possible to save on vitamin dobavkah.Pischevaritelnaya system of animals and birds adapted to feed revenues slightly acidic (pH of grain - 3.9-4.5). Chalk or limestone, getting into the body, not only deoxidize much food, but also neutralizes the acid gastric juice, disrupting the activity of gastric enzymes. Moreover, due to the high buffering activity sufficiently low dose of calcium carbonate to cause indigestion and sometimes even death of the young. Compared with chalk, limestone or dolomite flour (calcium carbonate), tricalcium phosphate has a higher absorption and lower buffer (alkaline) comprises emkost.Trikaltsiyfosfat ideal ratio of calcium and phosphorus, so its use as part of animal feed rations in the presence and improves feeding efficiency of the entire process The absence of side effects (Tricalcium phosphate limonnorastvorimy has no side effects even in the case of drug overdose and a half times) saves animals zdorovymi.Eto ecologically clean food product (much cleaner than their foreign counterparts), the quality of which is recognized by all breeders in the world.
The use of tricalcium phosphate in animal feed.
Modern science is well known that the most significant factors of mineral nutrition of animals is the two main elements - calcium and phosphorus. source of calcium for animal feed can be voluminous and numerous natural resources of minerals, common in many regions of the country. Solving the problem of animal phosphorus was and remains the most difficult problem. This is due to the fact that this macroelement no fossil sources. The voluminous little phosphorus feed. For example, in hay its concentration is lower than 5.9 times of calcium. The concentrated phosphorus feed relatively large. But its assimilation of these feed does not exceed 12-15% of the initial amount, and that it causes an enormous deficiency. Typically, more than 90% of the phosphorus in the related concentrates specific organic salts - phytates. Own enzymes that degrade these salts in the body of animals and birds not. And only in adult ruminants rumen microorganisms capable of releasing phosphorus from phytic compounds, making it affordable enough for zhivotnyh.Sovremennoe intensive pig and poultry farming is already inconceivable without the use of synthetic phosphorus additives. In world practice widely used mono-, di-, tri-calcium phosphate.
Tricalcium phosphate advantage over other mineral sources of phosphorus.
Tricalcium phosphate has the most high among the phosphate digestibility of calcium and phosphorus with minimal concentrations of heavy metals and harmful elements. The first proof of this - a high concentration of limonnorastvorimyh, assimilable form of the element.
It is known that contains tricalcium phosphate to 93% soluble phosphorus in 2% citric acid, whereas defluorinated phosphate concentration such forms rarely exceeds 78%. Naturally, the mono- and dicalcium soluble phosphorus ahead of tricalcium phosphate, but they are much more expensive, and the effect of their use slightly above.
Limonnorastvorimaya form of tricalcium phosphate is readily soluble in the gastrointestinal contents, even at low pH in the stomach. This fact suggests that tricalcium phosphate can be used in the feeding of young animals with a naturally low acidity, as well as at partial dysfunction of formation and release of acid in the stomach.
Phosphates in general, and tricalcium phosphate in particular, are better absorbed by the body of livestock and poultry, feeds than phosphorus. For example, if the phosphorus feed digestible cereal component by no more than 17-23%, the phosphate phosphor is able to pass into the bloodstream for more than 90% of its initial amount in the additive. Of these, tricalcium phosphate phosphorus can be considered the most digestible. Tricalcium phosphate is suitable for all kinds of farm animals and the majority of age and gender grupp.Skarmlivanie tricalcium phosphate effectively milk cows at a dose of 100g per head per day. Phosphates are effective against the backdrop senazhnokontsentratnyh rations when natural-fixed excess calcium in the diet background. Tricalcium phosphate figuratively speaking, "rescues" dairy animal from a mineral imbalance in the use of bagasse in the diet, by excessive calcium. Experienced animal science and scientists know that the wealth of phosphorus in the meager rations of nutritionally spring ensures that the live weight of the cows, as if "preserves" the animal, preparing it for intensive milk production during the transition to summer food. The daily cottage cows to 80-100g tricalcium phosphate for 1.5-2 months of the transition period, the spring provides the effect of keeping the body weight, does not allow for milking animals, allowing cows to provide increased productivity by at least 10-14% of laktatsiyu.Osobogo noteworthy use tricalcium phosphate in swine. In adult pigs using tricalcium phosphate manage to completely balance the ratio of these components in the diet. 40 g per head per day in the form of tricalcium phosphate - phosphorus welcome inclusion in a dose of 20 is adequate. This addition provides a significant increase in the absolute growth of young animals by 8.6% .In recent years, tricalcium phosphate have been widely used in the poultry industry. The most striking results were obtained in broiler production, where available tricalcium phosphate phosphor creates a truly "miracles." The rapid growth of broilers requires the formation of large quantities of energy-rich ATP compounds, each molecule of which contains three molecules of phosphoric acid. Increased phosphorus availability of tricalcium phosphate to cope more effectively with this problem. Tricalcium phosphate is added to the diet of broilers at the level of 1-2% by weight of the compound feed and receive consistently high growth effekt.V egg poultry use tricalcium phosphate provides a comparative increase in egg production in patients without additive to 20%. If we take into account the indicator of the level of digestible phosphorus, which in recent years strictly rationed, it will be possible to more accurately calculate the rate of administration of inorganic phosphate and thus its effect in the diet of laying hens will be real. This means that the rate of input of tricalcium phosphate in the feed of laying hens quantity strictly tied to the needs of poultry utilizable fosfore.Takim manner relatively cheap tricalcium phosphate may be regarded as the most valuable and effective source of mineral nutrients to the animal organism in its relatively low price. Its use allows you to easily balance the levels of phosphorus in the diets of all kinds of agricultural animals and significantly increase the productivity of animals.
Fodder calcium phosphate in compound feed chickens.
For modern poultry of highly productive crosses needed complete feed, balanced energy, protein and mineral veschestvam.Nedostatok minerals not only lowers the productivity of the birds, but also develop rickets and osteoporosis in young hens, which ultimately leads to a decrease in production efficiency. The main macro-scarce for birds are phosphorus and phosphorus kaltsiy.Potrebnost poultry (0.7%) are not provided by the mineral elements contained in the main components of the diet. It is believed that 60-65% of the phosphorus in the diet of broilers should be the so-called "available phosphorus". The latter include all non-plant phosphorus and 30% for the young (for laying hens) vegetable proiskhozhdeniya.Osnovnymi phosphorus sources of digestible phosphorus in compound feeds birds are animal feed - fish, meat and bone and bone meal. To cover the need for phosphorus birds diet should contain at least 8% of the animal feed. Reducing the production of animal feed origin and replacing them with vegetable protein leads to a reduction in rations available and increase the phytin phosphorus. To cover the deficit of phosphorus in animal diets industry has mastered the production of various phosphorus additives - sodium, calcium and ammonium. However, poultry practical interest only fluorine-free calcium phosphates, which are both a source of phosphorus and calcium.
Balancing phosphorus compound feed for poultry using the calcium phosphate in the form of mono-, di- and tri-calcium phosphate and fluorine-free phosphates from phosphate and apatite. total phosphorus availability of these drugs for poultry is 90-95%, and the phosphorus soluble in 2% citric acid solution - 100% .In Russia for birds first began to use the fluorine-free phosphates in the form of tricalcium phosphate feed. The chemical composition of fodder tricalcium phosphate 93% represented tricalcium phosphate, 5% are calcium and magnesium silicates, and 2% in the unmetabolized apatity.ZAO "Kormofos" mastered the production of tricalcium phosphate according to GOST 23999-80 and the first premium in the form of powder and grits with high solubility in 2% citric kislote.V task of research was to study the efficiency of animal production of tricalcium phosphate CJSC "Kormofos" in mixed fodders of highly cross broylerov.Issledovanie was held in EPH VNITIP in 2004 on broiler chickens Cobb-500 with daily up to 38 days of age by 38 goals in the group at the cellular growing parallel podgruppami.Usloviya content calves comply with the recommendations VNITIP. Feeding broilers was carried out with a complete feed for nutritional standards VNITIP ad libitum (2003). As test feed used tricalcium phosphate feed (TCP) produced JSC "Kormofos". The control group received the young in compound feed in the form of phosphorus defluorinated phosphate (DPP) made Ltd. "Industrial Group phosphorite."
Calcium phosphate fodder tricalcium brand produced by JSC "Kormofos" first class comprises 12.5% and 18.2% higher total phosphorus and 11.9, respectively; 16.8% soluble in citric acid. Higher grades of tricalcium phosphate contains phosphorus to total 0.8%, but most soluble in citric acid is 0.6% compared with defluorinated phosphate.
Phosphorus in the tricalcium phosphate to 92,3-95,2% is presented in the form of citrate form and so these phosphates are a valuable mineral food for young birds.
The use of tricalcium phosphate in the composition of complete feed ensures high safety ptitsy.Zhivaya mass of skilled young 38 days amounted 2281,6-2320,0 g greater than the control group of chickens on 3,8-5,5% .If use of tricalcium phosphate in the composition of complete feed noted good eating bird feed and reduction of feed cost per 1 kg of live weight gain on 1,1-4,0%. The best indicators of livestock were in the groups receiving higher sorta.Mineralizatsiya phosphate backbone at 38 days of age experienced young was within the physiological norm for this study did not vozrasta.V noted the influence of different grades of tricalcium phosphate in the chemical composition of the thoracic part of myshtsy.V complete feed tricalcium phosphate can be completely satisfy the needs of the birds in available phosphorus. The ration of broiler phosphate may be administered to 2-2.5% by weight of the feed, preferably in the form of grits.
Deftorfosfat (deftorfosfat fodder, tricalcium phosphate defluorinated).
Deftorfosfat feed additive contains calcium not less than 30%, phosphorous is not less than 18%, Sodium at least 5% and the auxiliary components. On appearance is melkogranulirovanny powder from light gray to dark brown, odorless, practically insoluble in vode.Deftorfosfat - a natural environmentally friendly mineral supplement that is made from natural raw phosphate rock and phosphoric acid with the addition of sodium hydroxide by hydrothermal sintering processing. With the new improved formula limonnorastvorimogo defluorinated phosphate, the additive can be used even at a reduced gastric acidity (hypo- and achlorhydria). Calcium is a macro element is required for the construction of the body of an animal cell membranes. It is involved in the conduct nerve impulses, muscle contraction in the initiation due to formation of actin-myosin complex is one of hematopoietic factors and coagulation, with insulin activates the entry of glucose into the cells. Calcium forms bone (up to 98% of calcium), supports muscle tone, prevents the premature development of osteoporosis, osteomalacia, postpartum eclampsia and paresis in cows, contributes to proper formation of the musculoskeletal system, which is especially important for young animals and birds. Calcium is a part of various enzyme systems that catalyze biochemical reactions in the body, moreover, increases the nonspecific resistance additives zhivotnogo.Pri use in producing animals daily gain increases muscle mass and improves the quality of meat products to yield 7 - 8.6%, milk - 10 - 14%, egg production in birds is increased on average by 20%, as well as the safety of eggs and nutritional properties of the finished product. The process of resorption and calcium absorption in the body is closely associated with the intake of phosphorus and vitamin D, at the optimum ratio of these elements of maximum absorption. Inorganic phosphorus compounds play an important role in maintaining acid-alkaline balance. Phosphorus is the most important part of the body of organic phosphorylated compounds such as nucleotides, nucleic acids, phospholipids, fosfoproteidy, vitamins, coenzymes and other compounds involved in various metabolic processes. Due to the peculiarities of the chemical structure, the phosphorus atoms are capable of forming high-energy bonds in the energy-rich compounds -. Adenosine triphosphate (ATP), creatine phosphate, etc. In the process of biological evolution phosphorus compounds become universal custodians of genetic information and transmit energy in all living systems. In terms of effects on the body of warm-blooded animal feed additive refers to low-hazard substances.
Assign to enrich and balance the rations of feeding animals and birds calcium and phosphorus. To improve the quality and quantity of the resulting animal products.
Tricalcium phosphate in dental and medical transplantation.
Osteoplastic synthetic inorganic materials (inorganic alloplasts) are a group of bioactive materials which are included in the ion exchange matrix and bone metabolism, and partially or completely replaced by bone in the process of regeneration are osteoconductive properties, i.e. are frame, which is replaced by bone tkanyu.Biosovmectimye materials - are materials having a non-biological origin and are used in medicine to achieve interaction with the biological system. Biocompatibility with bone can be considered as a material that is sufficiently inert with respect to osteoinduction active and relatively osteoconduction. Since the materials do not contain synthetic osteogenic cells and proteins - osteoinduktorov, they may not have the osteogenic svoystvami.Vse and osteoconductive grafts replacing bone defects, can be summarized as follows:
1. Autographs (human bone).
2. allografts (allogeneic transplants).
4. The explants (alloplastic grafts).
4.3. Tricalcium phosphate.
4.5. An alumina ceramic.
4.6. Combined with collagen preparations tricalcium phosphate or hydroxyapatite.
Bio-ceramic alloplasts composition is calcium phosphate in the proportion of calcium and phosphorus, which is characteristic for the living bone. Apply two types of calcium phosphate: hydroxyapatite and tricalcium phosphate. Hydroxyapatite and tricalcium phosphate are the backbone of naturally occurring inorganic component of bone. They are synthesized in vitro have a chemical composition Ca 10 (PO 4 ) 6 (OH) 2 and Ca 3 (PO 4 ) 2 , similar to natural. Therefore, calcium orthophosphate synthetic biocompatible materials are possible.
Tricalcium phosphate - a porous form of calcium phosphate. Tricalcium phosphate is used as a biological filler which is partly resorbed and replaced by bone. The transformation of tricalcium phosphate is a pivotal point of periodontal regeneration. This "scaffolding" for the formation of new bone, which is then replaced by newly formed bone. Kostepodobnaya tricalcium phosphate as the substance can be used in klinike.Nedostatkami tricalcium phosphate ceramics is that part of it is not absorbed, and is encapsulated by fibrous connective tissue and stimulates the formation of kosti.Iz due to limited availability, immune rejection and other problems related to the use of auto-c , allograft and xenograft, are increasingly used various implants. The implant - an artificial material or device that is surgically placed in organizm.V now as implants in trauma and orthopedics and dentistry is widely used bioceramics. The latter include: alumina, zirconia, titania, hydroxyapatite, tricalcium phosphate, bioactive glasses and glass-ceramics. Depending on the type of reaction in the body can be classified into bioceramics bioinert, bioactive, and dissolves in the body (resorbed) .Within easy calcium phosphate material such as hydroxyapatite, tricalcium phosphate, some compounds silicate glass and glass ceramic, bioactive materials are similar in composition human bone tissue. Recent contribute to the formation on the surface of the bone and the formation of the last strong chemical bonds (bioactive fixation). These bioactive materials are osteoconductive ceramic matrix causing adhesion morphogenetic proteins, osteoblast precursor cells, their proliferation and differentiation into ceramics is calcium phosphate osteoblasty.Bioaktivnaya osteointegriruemoy and in some cases - osteoinductive, that is largely determined by the geometrical characteristics of the implant. The presence and severity of bone formation on the surface and within the pores of the ceramic depends on numerous factors such as the size, shape, porosity, chemical composition, surface microstructure of the biomaterial, and others. One of the drawbacks of calcium phosphate ceramics is the low mechanical strength of this type of implant. Synthetic inorganic osteoplastic material β -trikaltsiyfosfat in dentistry. Indications Synthetic inorganic materials osteoplastic bone defects in the following:
- - Periodontal defects with medium and high osteogenic potential;
- - Horizontal and combined alveolar bone resorption;
- - Defects of the alveolar bone in the planning of further implant reconstruction;
- - Open and closed sinus lift;
- - Defects in the field of autologous bone fence;
- - Defects after apikektomy, kostektomy that granulemektomii;
- - Filling defects after root amputation (hemisection), tooth extraction;
- - Predimplantantnye defects.
β-tricalcium phosphate. - Granules macroporous, provide good adhesion, quick germination vessel, considerable osteoconductive surface;
- - Biodegradable products include ion exchange;
- - The material is completely resorbed, resorption medium term.
Recommended areas of application: orthopedics, traumatology, neurosurgery, dentistry.
The use in toothpastes.
The inorganic part of bone tissue of the tooth is made up of calcium orthophosphate [OFC].
Hydroxyapatite calcium [GAP; Ca 10 (PO 4 ) 6 (OH) 2 ] and β-tricalcium phosphate [TCP; Ca 3 (PO 4 ) 2 ] are the major mineral components of bone tissue. Because of the chemical similarity with biological calcified tissues, all orthophosphate are biocompatible materials. Despite the ever-growing use of calcium orthophosphate in medicine, there are very few papers describing the properties of not only the conventionally used calcium orthophosphate (β-tricalcium phosphate and hydroxyapatite), but also other biocompatible OFC.
One of the most important properties of calcium orthophosphate is their solubility in water because of their solubility can predict the behavior in the body. If FCS solubility, such as calcium hydroxyapatite, solubility less bone mineral component, it degrades extremely slowly. Calcium orthophosphate degradation rate in the body can be predicted in the following order:
MKFM> Tekfen = β-TCP> DKDF> DKF> β-TCP> Gran amorphous HAP> HAP, where:
MKFM - monocalcium phosphate
Tekfen - tetrakaltsy phosphate
β-TCP - β-tricalcium phosphate
DKFD - dicalcium phosphate dihydrate
β-TCP - β-tricalcium phosphate
Gran - precipitated GA
GAP - calcium hydroxyapatite
The most promising material as biodegradable deputy bone and drug carrier yavlyaetsyaosazhdenny calcium hydroxyapatite.
All calcium orthophosphate are antioxidants, and are approved for use as a food dobavki.V mainly calcium orthophosphate compounds studied until recently as materials, reducing bone. Synthetic calcium hydroxyapatite and β-tricalcium phosphate have the ability to replace the mineral phase is in contact with the bone and promote bone regeneration. Known as the ability of calcium hydroxyapatite and β-tricalcium phosphate to wound healing, hemostatics properties mitogenic effect.
Analysis of the literature in the field of dentistry showed that the hydroxyapatite and β-tricalcium phosphate lead to the normalization of the functional state of the dental pulp and dentin remineralization cause the bottom of the cavity. In the treatment of deep caries and pulpitis are a large number of drugs, but the most promising are the substances that provide dentin remineralization and stimulating odontotropnuyu function of dental pulp. Clinically confirmed that as a result, tissue structures are formed full tooth caries further stabilizing and oslozhneniy.Gidroksiapatit calcium and β-tricalcium phosphate are part of medical and prophylactic tooth-pastes, intended for the prevention and treatment of dental caries, periodontal disease and mucosa oral reduce hypersensitivity enamel. Toothpastes are multi-component systems consisting of abrasives, gelling, blowing, antibacterials, surfactants, and other biologically active substances. In toothpastes calcium orthophosphate referred to as abrasive components. It should be noted that the effectiveness of the toothpaste is mainly determined by the properties of the abrasive component. calcium hydroxyapatite and β-tricalcium phosphate co-production company "Zimtek" and CJSC "Almaztehnokristall" is a highly purified (high purity 99.96%), a biocompatible, easily absorbable powders of different crystal structure, the degree of dispersion, the hardness at neutral pH.
New biocompatible materials based on calcium orthophosphates are also designed using mirokapsulirovaniya technology. Microencapsulation of bioactive substances in biodegradable matrix is one of the ways to get a long-acting materials, controlled release, multi-purpose and long-term storage. The technical result is to obtain microgranules which are included in the biopolymer matrix of fine crystals of high purity calcium hydroxyapatite and tricalcium phosphate with special characteristics with the possibility of further use for specific purposes in the manufacture of cosmetic, pharmaceutical and food products. The use of gelling biopolymers consisting of natural origin to form microgranules matrices will provide toothpastes in the form of pastes, gels having fundamentally new functional properties.
Water defluorination tricalcium phosphate.
One method of removing fluorine from water it is a freshly precipitated tricalcium phosphate sorption. In VODGEO Institute of studies have been conducted on removal of water from the fluorine-precipitated tricalcium phosphate, obtainable by introducing lime water in a 1% phosphoric acid solution with continuous stirring.
Binding occurs through the reaction of fluorine When treated water pass through the layer of suspended sediment fluorine content of tricalcium phosphate in the water is reduced from 5 to 1 mg / l tricalcium phosphate at a flow rate of 30 mg per 1 mg remote ftora.Vo prevent easy removal of the precipitate of tricalcium phosphate flow rate rising to the weighted area sediment is allowed no more than 0.6-0.7 mm / s.Pri use of tricalcium phosphate for water purification from fluorine can be used by one of the processing circuits represented in the previous risunke.Tehnologiya water treatment is sleduyuschem.Dlya produce tricalcium phosphate in the vertical mixer is introduced or a mortar, and then phosphoric acid solution, the two solutions simultaneously or a calculation amounts required for the formation of trikaltsiyfosfata.Posle water is supplied to the clarifier and passes through the layer of floating sludge tricalcium phosphate, wherein the fluorine removal process occurs with the formation of the sparingly soluble fluoride which precipitates in sediment in the composition of plants except osadkouplotnitele.V clarifiers should include filters for retention of small flakes, handed down the flow of water from the water after disinfection osvetliteley.Filtrovannaya pumps lifting II served in the consumer network. A significant disadvantage of water purification from fluorine by this scheme is the difficulty of regeneration a precipitate of tricalcium phosphate and therefore significant flow of phosphoric acid to prepare a new suspension. Phosphoric acid consumption per 1,000 m³ of water with a fluorine concentration of 5 mg / L was 0.15 m.